This announcement could give you for 1 last update 2020/02/18 some heartburn.This announcement could give you some heartburn.
The U.S. Food and Drug Administration (FDA) has issued warning about a commonly-used type of heartburn medication. And this warning included some impure thoughts. Testing has found batches of ranitidine to be contaminated with an impurity called NDMA. If you think that this news doesn’t apply to you because you take Zantac, think again. Zantac is actually one brand name for ranitidine. Ranitidine can decrease acid secretion in your stomach acid by blocking histamine H2 receptors and therefore is frequently used to treat stomach ulcers and heartburn, otherwise known as gastroesophageal reflux disease or GERD, which rhymes with turd.
NDMA doesn’t stand for North Dakota-Massachusetts but instead is short for N-nitrosodimethylamine. It’s classified as a probable human carcinogen, meaning that there is a good chance that the compound can cause cancer if present at high enough levels. If you’ve heard of this the 1 last update 2020/02/18 chemical compound before, it may be because this was the contaminant found in certain blood pressure medications, Angiotensin II Receptor Blockers (ARBs), last year, as I covered previously for Forbes. NDMA doesn’t stand for North Dakota-Massachusetts but instead is short for N-nitrosodimethylamine. It’s classified as a probable human carcinogen, meaning that there is a good chance that the compound can cause cancer if present at high enough levels. If you’ve heard of this chemical compound before, it may be because this was the contaminant found in certain blood pressure medications, Angiotensin II Receptor Blockers (ARBs), last year, as I covered previously for Forbes.
If you recall, NDMA contamination did result in recalls of some of these blood pressure medication. So the obvious questions are will ranitidine be recalled, what should you do if you are taking ranitidine, and what rhymes with ranitidine? The answers are “no, not at the present moment”, “talk to your doctor and possibly select an alternative medication”, and “passionate scene or plasma choline.”
The levels of NDMA detected in the ranitidine were apparently quite low, lower than the levels found in the blood pressure medications that were recalled. Ingesting such levels alone probably won’t put you at risk for developing cancer. There is a good chance that you have already been exposed to NDMA since it can be a contaminant in your environment, food, and water. What matters is how much goes into your body over time. As a result, it is a good idea to try to minimize your intake of NDMA.
Heartburn Remedies Disease (🔥 Herbs) | Heartburn Remedies 13 Surprisinghow to Heartburn Remedies for Therefore, while the FDA “is not calling for individuals to stop taking ranitidine at this time,” you may want to find alternatives if you can. Ranitidine is certainly not the only medication available for heartburn, stomach ulcers, and other stomach acid-related problems. There are other H2-receptor blockers that work by the same mechanism as ranitidine. These include nizatidine (sold via the brand name Axid), famotidine (Pepcid, Pepcid AC), and cimetidine (Tagamet, Tagamet HB). All of these also sort of rhyme with “passionate scene” and “plasma choline,” so you won’t miss much switching to them.
Heartburn Remedies GERD Diet (🔥 Home Remedies For) | Heartburn Remedies Heartburn Treatmentshow to Heartburn Remedies for If you are on ranitidine, check with your doctor. You may not even need to be on such medications. For example, for heartburn, there are a number of options including lifestyle modifications such as eating less oily or acidic foods, cutting down on your caffeine and alcohol intake, adjusting when and how you sleep, and wearing more loose-fitting clothes that don’t compress your tummy and force acid up into your esophagus. So ease off on wearing Spider Man costumes and munching on deep-fried tomatoes and drinking Iced Irish Coffee while hanging upside down.
Meanwhile, stay tuned as the FDA continues its investigation.
With all the blood pressure medication recalls over this past year, this latest FDA announcement does seem like déjà vu all over again. The question is whether drug manufacturers are maintaining appropriate safety and quality control measures and how these are being monitored. As more and more manufacturing is being done overseas, it can be harder and harder to keep track of what’s happening. It can be tempting to cut manufacturing costs to save money but producing drugs is not the same as making handbags. Even a small mistake with a medication can have serious consequences. The thought of that alone could give you heartburn.
September 19, 2019 UPDATE: Due to these aforementioned concerns, Novartis has stopped shipping their generic form of Zantac. Before you say, “oh my GERD,” Novartis is describing this as a “precautionary distribution stop.” Investigations are still underway.
Also, note that this is not a recall. So if you try to return or mail back any ranitidine that you have already purchased, you ain’t going to get anything in return.
For now, Sanofi, the makers of the original Zantac, has not announced any plans to stop distribution of the medication. As they say about evolving situations and guitars, stay tuned.
I am a writer, journalist, professor, systems modeler, computational and digital health expert, avocado-eater, and entrepreneur, not always in that order. Currently, I...